Categories
Biology

The Silent Scream of MicroRNA

Genetic disposition can affect conditions–

they can turn visions to reality,

and even turn the key

with regards to life, strife, or physical might

weight, height, colors in sight–

genetic disposition affects perception.

Genetic silencers take aim and fire,

but only on sequences that aren’t required.

If you are looking for an influence,

micro RNA makes the difference.

These micro RNA’s run the streets

leaving behind ribosome’s

as I am making this beat–

when it comes to gene regulation,

other strains of protein better just take a seat.

These back-channel messengers are super-efficient,

completely eliminating a need for rendition.

Genetic silencers take aim and fire,

but only on sequences that aren’t required.

If you are looking for an influence,

micro RNA makes the difference.

Categories
Biology

Research proposal article: Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

Unanswered questions in this research article pertain towards underscoring the protumorigenic effects of miRNA loss-of-function; why cells were expressed at approximately equivalent levels in normal liver and tumors; reasons why miR-34a was strongly upregulated in liver tumors; what influences antitumorigenic properties and potential therapeutic utility for liver cancer in vitro and in vivo (Kota et.al, 2009)