Categories
Medicine and Health

Ketamine as a Novel Therapy for Depression

NMDA Receptor Antagonists and their Antidepressant Activity

Objectives

Ø  To describe the singling pathways of NMDA receptors in the brain cells.

Ø  To highlight the mechanism of action of traditional SSRIs

  • To differentiate the singling pathways of NMDA receptors antagonists and SSRIs
Categories
Criminal Justice

Privatization of Prisons

Introduction

Privatization of various services by the government has been necessitated by the need to have more efficiency and quality within the government. For many years, most of the government were deemed inefficient due to the bureaucracy and the immense time taken to get some of these services. Therefore, the government has had to partner with the private sector to boost its capacity in terms of management and finances (Lindsey, Mears & Cochran, 2016). Nevertheless, the issue of privatization of government services has elicited sharp and conflicting viewpoints as far as transparency and accountability are concerned. Some people feel that the government tends to lose control once it privatizes it transfer its services to private players (Volokh, 2017). Additionally, the level of accountability that is attached to government agencies drastically reduces once private agencies take over these services. One sector that the US government has managed to privatize is the correctional facilities department, specifically prisons.

Categories
Literature

Persepolis: The Story of a Childhood and Persepolis 2: The Story of a Return

Young people begin discovering things about themselves such as interests, hobbies, and dreams as they grow up. However, some forces more powerful than them may obstruct their freedom. These forces may mold and shape the youth in what they think is right for them even though they do not like it.  These forces take away their freedom. “Persepolis depicts Iran before, during, and after the 1979 Iranian Revolution and the rise of the autocratic Islamic state under Ayatollah Khomeini. The beginning of Persepolis I: The Story of a Childhood is narrated by eight-year-old Marji who is learning to navigate the new rules of the Islamic regime built upon the foundations of an Islamic republic and sharī‘ah law. As the narrative progresses Marji grows increasingly resistant to the regime—a resistance that is supported by her parents—until by the end of the first book she is an adolescent in the airport leaving for Austria. The second book, Persepolis II: The Story of a Return, picks up once Marji is in Austria and narrates her struggle to find her identity in exile. In a mirror image of Book I, Book II ends with Marji in the airport leaving her family to return to a final, self-imposed exile in Europe.

Categories
Accounting

Jonson and Johnson Company Financial History

Income Statement (in Millions)

  2015 2016 2017
Sales for customers 70,074 71,890 76,450
Cost of products sold (21,536) (21,685) (25384)
Gross profit 48,538 50,205 51,096
Selling, marketing and administrative expenses (21,203) (19,945) (21,420)
Research and development  expense (9,046) (9,095) (10,554)
In-process research and development (224) (29) (408)
Restructuring (509) (491) (309)
Operating earnings 17,556 20,645 18,405
Interest income 128 368 385
Interest expense ,net of portion capitalized (552) (726) (934)
Other income(expense)net 2,064 (484) (183)
Earnings before provision for taxes on income 19,196 19,803 17,673
Provision for taxes on income (3,787) (3,263) (16,373)
Net earnings 15,409 16,540 1,300
Categories
Sociology

Social Life

Introduction

Gender refers to the state of being female or male. The term is used social as well as cultural aspects of life to differentiate between masculinity and feminism.  A race, on the other hand, refers to a group of individuals with specific physical characteristics that are similar. Most of these individuals belong to the same area and shares a common language. A social class, on the other hand, refers to the particular division of the society based on the economic as well as the financial status of individuals. The three aspects are critical in one`s life as well as the community in that on identifying one`s identity, and a person can develop strong relationships with other people in the society (Morris et al 340).

Categories
Business

Memorandum

TO:

FROM:

SUBJECT:

DATE:

OVERVIEW

This paper is concerning the removal of NAFTA and the formulation of an industry wide strategy to protect California’s agricultural industry. NAFTA has come under fire from the American government due to perceptions of unfair trading practices that benefit Mexico more than the United States; regardless of the truth of these assumptions, the political conversation surrounding the trade agreement has led to many to believe that NAFTA will be revoked. This will have serious effects on California’s agricultural sector, which is reliant upon intercontinental trade in certain goods to remain competitive. Business strategies were constructed by estimating the likelihood of each possibility and comparing them to the expected result, as well as through predicting market behavior.

Categories
Computer Science

Effectiveness of FlexRR

Abstract

The purpose of this study is to test the effectiveness of FlexRR is a straggler mitigation technique in over the Parameter Server for important Machine Learning(ML) strategies including Matrix Factorization (MF), Logistic Regression (LR), and Latent Dirichlet Allocation (LDA). The study was conducted to test FlexRR as a straggler mitigation technique over different Machine Learning Algorithm such as MF/LR/LDA. It thus employed the Bulk Synchronous Parallel (BSP) computational model to examine the straggler problem in Parameter Server on Iterative Convergent Distributed Machine Learning. Moreover, the current research analyzes the experimental arrangement of the parameter server strategy concerning the parallel learning problems by injecting universal straggler patterns and executing latest mitigation techniques. The findings of the study are significant in that as they will provide the necessary platform for conducting further research into the problem and allow the researcher to compare different methods for various applications. The outcome is therefore expected to facilitate the development of new techniques coupled with new perspectives in addressing this problem.